Anti-inflammatory Properties of Mitragyna Speciosa Extract

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Raja Aziddin R.E
Mustafa M.R
Mohamed Z
Mohd. M.A

Abstract

The anti-inflammatory property of the alkaloid extract from the leaves of Mitragyna speciosa was evaluated on the basis of the inhibitory effect of the extract on carrageenan-induced hind paw edema in rat. This extract when administered by intra peritoneal injection at a concentration of 50 mg/kg produced almost 100% inhibition of the carrageenan-induced paw edema 1 hour after administration. The inhibition was maintained at about 60%, 7 hours after administration. These findings suggest that the alkaloid extracts of the leaves of Mitragyna speciosa possess potent anti-inflammatory properties.

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How to Cite
Aziddin R.E, R., M.R, M., Z, M., & M.A, M. (2005). Anti-inflammatory Properties of Mitragyna Speciosa Extract. Malaysian Journal of Science, 24(1), 191–194. Retrieved from http://ijie.um.edu.my/index.php/MJS/article/view/8971
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Original Articles