Synthesis and characterisation of Mo(IV) complexes of 2,3-dihydroxybenzaldehyde Schiff Bases and their activity against cancer cell lines

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Published: Apr 26, 2001

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Sharifah Rohaiza, S.O
Hapipah, M.A
Mohd Zawawi, Y
Sharifuddin, M.Z
Norhanom, A.W
Rahuma, S.M

Abstract

Schiff base ligands (SB) have been prepared by condensation of 2,3-dihydroxybenzaldehyde with aromatic amines in either absolute ethanol or methanol. The products reacted with MoCl5 in MeCN in a 1:1 stoichiometry in the presence of triethylamine to afford [MoCl2(SB)2]. The Schiff bases and the molybdenum complexes have been characterized by elemental analysis, IR,1H NMR and 13C NMR spectroscopic methods. The anti-tumour test was conducted on the ligands and the complexes. The tumour growth inhibitory activity of the Schiff bases and their derivatives are reported.

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How to Cite
Rohaiza, S.O, S., M.A, H., Zawawi, Y, M., M.Z, S., A.W, N., & S.M, R. (2001). Synthesis and characterisation of Mo(IV) complexes of 2,3-dihydroxybenzaldehyde Schiff Bases and their activity against cancer cell lines. Malaysian Journal of Science, 20(1), 103–111. Retrieved from http://ijie.um.edu.my/index.php/MJS/article/view/8786
Issue
Vol. 20 No. 1 (2001)
Section
Original Articles

Licensee MJS, Universiti Malaya, Malaysia. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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