FABRICATION AND CHARACTERIZATION OF BREAST PHANTOM BASED ON GELATIN-GLYCERIN-TiO2 FOR A CONTINUOUS-WAVE DIFFUSE OPTICAL TOMOGRAPHY

Abstract

In this paper,  the fabrication and characterization of breast phantom based on gelatin-glycerin-TiO₂ as breast simulation tissue is proposed and investigated. A sample preparation was done by mixing 3 grams of gelatin per 10 ml of saline. The sample was added with glycerin with four different concentrations of 85%, 90%, 95% and 100% as sample A, B, C and D respectively. The sample D is optimum as it was able to survive at room temperature for 126 hours. Subsequently, sample D was added by TiO₂ given variations of 0.010 grams, 0.015 grams, 0.020 grams and 0.025 grams. All samples were tested for its homogeneity and absorption coefficient using Continuous Wave Diffuse Optical Tomography (CW-DOT) with laser wavelengths of 780, 808 and 830 nm. The results showed that the optimum sample characterization was achieved at wavelength of 830 nm with TiO₂ variation of 0.025 grams. The absorption coefficient breast phantom was obtained at 0.167 mm^-1. Phantom based on gelatin-glycerin-TiO₂ can be applied as material replacement of breast for test object in CW-DOT.